Saint Francis University (SFU) is a private Catholic liberal arts university in Loretto, Pennsylvania. It was founded in 1847 and conducted under the tradition of the Franciscan Friars of the Third Order Regular. The university is situated on 600 acres (243 ha) in the forests and farmland of Loretto.

Saint Francis College was established in 1847 by six Franciscan teaching Brothers from Mountbellew, Ireland, who had been given land in Loretto by Michael O'Connor, the first Bishop of Pittsburgh, to establish a school. The university was one of the first Catholic universities in the United States and the first Franciscan college in the nation. Although it originally only admitted males, it became one of the first Catholic Universities to become co-educational. Loretto is the site of the first English-language Roman Catholic settlement established west of the Allegheny Front, in what is now the United States, by Demetrius Augustine Gallitzin in 1799.

In 2001 Saint Francis College was approved to change to become a university by the Commonwealth of Pennsylvania and renamed to Saint Francis University.

St. Francis University